Listar por autor "Guerrero Setas, David"

Absence of nuclear p16 is a diagnostic and independent prognostic biomarker in squamous cell carcinoma of the cervix

Mendaza Lainez, Saioa

; Fernández Irigoyen, Joaquín

; Santamaría, Enrique; Zudaire, Tamara; Guarch, Rosa; Guerrero Setas, David (MDPI, 2020) Artículo / Artikulua

The tumor-suppressor protein p16 is paradoxically overexpressed in cervical cancer (CC). Despite its potential as a biomarker, its clinical value and the reasons for its failure in tumor suppression remain unclear. Our ...

Approaching the epigenome of triple negative breast cancer to identify new biomarkers

Mendaza Lainez, Saioa

(2020) Tesis doctoral / Doktoretza tesia

El cáncer de mama (CM) es la neoplasia más frecuente en todo el mundo y la primera causa de muerte por cáncer en mujeres. El cáncer de mama triple negativo (CMTN) representa el 10-20% de todos los CM diagnosticados y es ...

Búsqueda de nuevos biomarcadores epigenéticos en cáncer de mama triple negativo

Ulazia Garmendia, Ane (2016) Trabajo Fin de Máster/Master Amaierako Lana

Introducción El estudio de las alteraciones epigenéticas contribuye a la caracterización del subtipo triple negativo (TN) de cáncer de mama (CM). Objetivos Identificar genes diferencialmente metilados entre CM TN y ...

CDH22 hypermethylation is an independent prognostic biomarker in breast cancer

Martín Sánchez, Esperanza; Mendaza Lainez, Saioa

; Ulazia Garmendia, Ane; Monreal Santesteban, Iñaki; Córdoba Iturriagagoitia, Alicia; Vicente García, Francisco; Blanco Luquin, Idoia; Cruz, Susana de la; Aramendia, Ana; Guerrero Setas, David (BioMed Central, 2017) Artículo / Artikulua

Background: Cadherin-like protein 22 (CDH22) is a transmembrane glycoprotein involved in cell-cell adhesion and metastasis. Its role in cancer is controversial because it has been described as being upregulated in ...

A DNA methylation-based gene signature can predict triple-negative breast cancer diagnosis

Mendaza Lainez, Saioa

; Guerrero Setas, David; Monreal Santesteban, Iñaki; Ulazia Garmendia, Ane; Córdoba Iturriagagoitia, Alicia; Cruz, Susana de la; Martín Sánchez, Esperanza (MDPI, 2021) Artículo / Artikulua

Triple-negative breast cancer (TNBC) is the most aggressive breast cancer (BC) subtype and lacks targeted treatment. It is diagnosed by the absence of immunohistochemical expression of several biomarkers, but this method ...

Next-generation sequencing of bile cell-free DNA for the early detection of patients with malignant biliary strictures

Arechederra, María; Rullán, María

; Amat Villegas, Irene

; Oyón, Daniel; Zabalza, Lucía; Elizalde, María; Latasa, Maria Ujue; Mercado Gutiérrez, María R.; Ruiz-Clavijo, Daniel; Saldaña, Cristina; Fernández-Urién Sainz, Ignacio; Carrascosa, Juan; Jusué, Vanesa; Guerrero Setas, David; Zazpe, Cruz; González Borja, Iranzu; Sangro, Bruno; Herranz, José M.; Purroy, Ana; Gil, Isabel; Nelson, Leonard J.; Vila, Juan J.; Krawczyk, Marcin; Zieniewicz, Krzysztof; Patkowski, Waldemar; Milkiewicz, Piotr; Cubero, Francisco Javier; Alkorta Aranburu, Gorka; Fernández-Barrena, Maite G.; Urman, Jesús M.; Berasain, Carmen; Ávila, Matías A. (BMJ Publishing Group, 2021) Artículo / Artikulua

Objective: despite significant progresses in imaging and pathological evaluation, early differentiation between benign and malignant biliary strictures remains challenging. Endoscopic retrograde cholangiopancreatography ...

A novel prognostic biomarker panel for early‐stage colon carcinoma

Azcue Sanromán, Pablo; Guerrero Setas, David; Encío Martínez, Ignacio

; Ibáñez Beroiz, B.

; Mercado Gutiérrez, María R.; Vera García, Ruth; Gómez Dorronsoro, María Luisa (MDPI, 2021) Artículo / Artikulua

Molecular characterization of colorectal cancer has helped us understand better the biology of the disease. However, previous efforts have yet to provide significant clinical value in order to be integrated into clinical ...

PD-L1 as a prognostic factor in early-stage colon carcinoma within the immunohistochemical molecular subtype classification

Azcue Sanromán, Pablo; Encío Martínez, Ignacio

; Guerrero Setas, David; Suarez Alecha, Javier; Galbete Jiménez, Arkaitz

; Mercado Gutiérrez, María R.; Vera García, Ruth; Gómez Dorronsoro, María Luisa (MDPI, 2021) Artículo / Artikulua

Colorectal cancer (CRC) is a very heterogeneous disease. Efforts to characterize and search for biomarkers for these patients are currently ongoing in the hope of establishing a more targeted therapeutic approach. The role ...